3D-GNOME - 3D chromatin organization webservice

3D genome organization plays a critical role in its functioning. The recent advent of Chromosome Conformation Capture (3C) based techniques such as ChIA-PET and Hi-C allows us to investigate this organization by means of either creating a contact map (or heatmap) representing the frequency of interactions between pairs of genomic loci, or by identifying a set of strong, confident interactions.

This webservice allows for creating 3D models of the genomic regions selected by the user and their interactive visualization, as well as for a simple explorative data analysis by means of data statistics (for example the number of singletons and PET clusters contained in the region, or their average and maximal length), heatmaps and plots (interactions length distribution or the distribution of interacting loci across the selected region).

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